Cumulative Evidence That Mesenchymal Stem Cells Promote Healing of Perianal Fistulas of Patients With Crohn's Disease–Going From Bench to Bedside

In this month’s issue of Gastroenterology, Molendijk et al1 present their article entitled “Allogeneic Bone Marrow-derived Mesenchymal Stromal Cells Promote Healing of Refractory Perianal Fistulas in Patients with Crohn's Disease.” The authors present a potential new treatment option: mesenchymal stem/stromal cells (MSCs) for patients with refractory perianal Crohn’s disease (CD). Perianal fistulas are a common manifestation of CD affecting about 25% of patients2 and are a particularly destructive and morbid complication that frequently causes purulent drainage, pain, and sometimes fecal incontinence.

Source: Gastroenterology - August 23, 2015 Category: Gastroenterology Authors: Damian Garcia-Olmo, David A. Schwartz Tags: Editorial Source Type: research