Penn study demonstrates genes' major role in skin and organ development

(University of Pennsylvania School of Medicine) Knocking out one or both crucial regulatory genes caused cleft lip, skin barrier defects, and a host of other developmental problems in mice, hinting that abnormalities in these molecular pathways could underlie many birth defects that are presently not well understood. The two closely related regulatory genes are active in the normal development of mammals and govern how RNAs produced from the genes are joined to make final versions of the encoded protein.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news