Next-generation sequencing for genetic testing of familial colorectal cancer syndromes
Conclusions
The multiplex NGS approach has the advantage of analyzing multiple genes in multiple samples simultaneously, requiring only a reduced number of Sanger sequences to resolve homopolymeric DNA regions not adequately assessed by NGS. The implementation of NGS approaches in routine diagnostics of familial CRC is cost-effective and significantly reduces diagnostic turnaround times.
Source: Hereditary Cancer in Clinical Practice - Category: Cancer & Oncology Source Type: research
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