KLF2 exerts antifibrotic and vasoprotective effects in cirrhotic rat livers: behind the molecular mechanisms of statins

Conclusions
Exogenous hepatic KLF2 upregulation improves liver fibrosis, endothelial dysfunction and portal hypertension in cirrhosis.

Source: Gut - August 7, 2015 Category: Gastroenterology Authors: Marrone, G., Maeso-Diaz, R., Garcia-Cardena, G., Abraldes, J. G., Garcia-Pagan, J. C., Bosch, J., Gracia-Sancho, J. Tags: Cirrhosis Hepatology Source Type: research