Uncovering novel drug targets for bipolar disorder: a Mendelian randomization analysis of brain, cerebrospinal fluid, and plasma proteomes

CONCLUSIONS: Our study identified druggable proteins for BD, including MCTP1, DNM3, and PDF in the brain; CTSF, AGRP, and FRZB in cerebrospinal fluid; and LMAN2L, NCAM1, and TIMP4 in plasma, delineating promising avenues to development of novel therapies.PMID:38720515 | DOI:10.1017/S0033291724001077

Source: Psychological Medicine - May 9, 2024 Category: Psychiatry Authors: Tingting Jia Tiancheng Liu Shiyi Hu Yongjun Li Peixi Chen Fengqin Qin Yongji He Feng Han Chengcheng Zhang Source Type: research