Targeted metabolomics combined with machine learning to identify and validate new biomarkers for early SLE diagnosis and disease activity

CONCLUSION: This study indicated that the tricarboxylic acid cycle might be associated with SLE drug therapy. We identified 8 diagnostic models biomarkers and 2 biomarkers that could be used to identify initial SLE and distinguish different activity degree, which will promote the development of new tools for the diagnosis and evaluation of SLE.PMID:38710348 | DOI:10.1016/j.clim.2024.110235
Source: Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research