Synthesis, In Silico Prediction, and In Vitro Evaluation of Anti-tumor Activities of Novel 4'-Hydroxybiphenyl-4-carboxylic Acid Derivatives as EGFR Allosteric Site Inhibitors

CONCLUSION: Compound S4 is a promising EGFR tyrosine kinase allosteric inhibitor that warrants further research.PMID:38693732 | DOI:10.2174/0109298673305163240427065543

Source: Current Medicinal Chemistry - May 2, 2024 Category: Chemistry Authors: Wurood A Shihab Ammar A Razzak Kubba Lubna H Tahtamouni Khaled M Saleh Mai F AlSakhen Sana I Kanaan Abdulrahman M Saleh Salem R Yasin Source Type: research