Effective bridging strategies prior to infusion with tisagenlecleucel results in high response rates and long-term remission in relapsed/refractory large B-cell lymphoma: findings from a German monocentric study

CONCLUSION: The study underscores the importance of minimal tumor burden at CAR-T initiation, emphasizing the need for suitable bridging regimens. The findings advocate for clinical trials and further real-world analyses to optimize CAR-T cell therapy outcomes by identifying the most effective bridging strategies.PMID:38693452 | DOI:10.1007/s00432-024-05765-8

Source: Cell Research - May 1, 2024 Category: Cytology Authors: Farina Eigendorff Irina Filimonova Sebastian Scholl Anne Sayer-Klink Silke Rummler Christa Kunert Klaus Pietschmann Andrea Wittig Andreas Hochhaus Ulf Schnetzke Source Type: research