Factors affecting heterogeneity in breast cancer microenvironment: A narrative mini review
Int Rev Cell Mol Biol. 2024;385:211-226. doi: 10.1016/bs.ircmb.2024.01.002. Epub 2024 Feb 15.ABSTRACTBreast cancer (BC) heterogeneity is a key trait of BC tumors with crucial implications on tumorigenesis, diagnosis, and therapeutic modalities. It is influenced by tumor intrinsic features and by the tumor microenvironment (TME) composition of different intra-tumoral regions, which in turn affect cancer progression within patients. In this mini review, we will highlight the mechanisms that generate cancer heterogeneity in BC and how they affect the responses to cancer therapies.PMID:38663960 | DOI:10.1016/bs.ircmb.2024.01.002
Source: International Review of Cell and Molecular Biology - Category: Cytology Authors: Anirban Ganguly Sumit Mukherjee Kaushiki Chatterjee Sheila Spada Source Type: research
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