Comparing brain activation in two subtypes of task-specific focal dystonia during dystonia-related and unrelated tasks: An fMRI study

Background: Task-specific focal dystonia [TSFD] is characterized by involuntary, localized muscle contractions during specific motor activities (e.g., writing in focal hand dystonia [FHD], speaking in laryngeal dystonia [LD]). It is unclear if a shared central mechanism contributes to different body regions being affected in TFSD subtypes. Previous work using task-based functional magnetic resonance imaging (fMRI) has indicated abnormal activation in body-region-specific sensorimotor networks separately in FHD and LD against controls [CTL].

Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: B.P. Huynh, Y. Wang, M. Chen, E. Narinsky, Y.-L. Kuo, T.J. Kimberley Source Type: research