Head Position During Sleep: Potential Implications for Patients with Neurodegenerative Disorders

Background: In 2015, Lee et al. observed sleeping position influenced the efficiency of glymphatic clearance of β-amyloid in anesthetized rats with the lateral position being more efficient than supine. In 2018, Levendowski et al. reported supine sleep> 2-hours per night was associated with neurodegenerative disorders (NDD) independent of age, sex, obstructive sleep apnea, and snoring. In 2019, Simka et al. revealed that in lateral positions the internal jugular vein above the heart partially collapses to optimize cerebral venous outflow and glymphatic clearance while in the supine position both internal jugular veins are open.
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Source Type: research