High circulating dipeptidyl peptidase 3 predicts mortality and need for organ support in cardiogenic shock: An ancillary analysis of the ACCOST-HH trial

Cardiogenic shock (CS) can be defined as a state of persisting low cardiac output associated with insufficient organ perfusion. Acute myocardial infraction (AMI) is its most frequent cause although up to 50% of all CS might be related to other etiologies including acute decompensated heart failure, valvular abnormalities, severe arrhythmia, myocarditis, septic cardiomyopathy etc... (1,2). Despite contemporary management, CS is still burdened with high mortality ( ∼30-50% in-hospital mortality) and efforts to improve outcome are hampered by the difficulty of individual risk stratification and the lack of targetable pathways (1).

Source: Journal of Cardiac Failure - April 29, 2024 Category: Cardiology Authors: Adrien Picod, Hugo Nordin, Dominik Jarczak, Tanja Zeller, Claire Oddos, Karine Santos, Oliver Hartmann, Antoine Herpain, Alexandre Mebazaa, Stefan Kluge, Feriel Azibani, Mahir Karakas Source Type: research