Acute Dapagliflozin Administration Ameliorates Cardiac Surgery-Associated Acute Kidney Injury in a Rabbit Model

CONCLUSIONS: Acute intravenous administration of dapagliflozin protects against CPB-induced AKI. Dapagliflozin may have direct renoprotective effects in renal tubular cells.PMID:38658352 | DOI:10.1253/circj.CJ-23-0864

Source: Circulation Journal - April 24, 2024 Category: Cardiology Authors: Kensaku Matsuda Hiroshi Mitsuo Takuya Nishijima Hikaru Uchiyama Tobuhiro Nita Shogo Matsunaga Noriko Fujimoto Tomoki Ushijima Yusuke Ando Meikun Kan-O Gen Shinohara Satoshi Kimura Hiromichi Sonoda Akira Shiose Source Type: research