Morphometric Integration of Brain Networks in Young Children Exposed to Maternal Depression in a South African Birth Cohort

Perinatal maternal depression is a mental health concern that disproportionately impacts children in low- and middle-income countries. Altered morphometry of frontal and limbic brain regions has been recorded in exposed children, mostly in high-income settings. The current study investigated morphometric integration between frontolimbic regions, an index of structural brain connectivity, after maternal depression exposure in two-to-three-year-old children from a South African birth cohort.

Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Nynke A. Groenewold, Richard A.I. Bethlehem, Alyssa R. Amod, Emmanuel C. Nwosu, Farai Mberi, Catherine J. Wedderburn, Jennifer A. Pellowski, Annerine Roos, Heather J. Zar, Kirsten A. Donald, Dan J. Stein, Jonathan C. Ipser Source Type: research