The SR-B1 ΔCT/LDLR KO mouse: A new tool to shed light on coronary artery disease.

Coronary artery disease (CAD) is known to be one of the leading causes of death in humans [1]. It occurs when atherosclerotic lesions gradually build up in the coronary arteries, leading to a narrowing or obstruction of these arteries, the function of which is to supply oxygenated blood and nutrients to the heart [2]. CAD can result in a range of clinical presentations, with mild symptoms such as chest pain or shortness of breath, to life-threatening conditions, namely myocardial infarction [2].
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research