Establishment of Human Pituitary Neuroendocrine Tumor Derived Organoid and Its Pilot Application for Drug Screening

CONCLUSION: The established PDOs, retaining typical features of parental tumors, indicate a translational significance in innovating personalized treatment for refractory PitNETs.PMID:38656317 | DOI:10.1210/clinem/dgae228

Source: The Journal of Clinical Endocrinology and Metabolism - April 24, 2024 Category: Endocrinology Authors: Run Cui Hao Duan Wanming Hu Chang Li Sheng Zhong Lun Liang Siyu Chen Hongrong Hu Zhenqiang He Zhenning Wang Xiaoyu Guo Zexin Chen Cong Xu Yu Zhu Yinsheng Chen Ke Sai Qunying Yang Chengcheng Guo Yonggao Mou Xiaobing Jiang Source Type: research