Viruses, Vol. 16, Pages 642: Monitoring HPV Prevalence and Risk Cofactors for Abnormal Cytology in the Post-Vaccination Period among Croatian Women

In this study, a total of 321 women attending gynecological care were evaluated. Relevant medical and demographic information, including cytology, were collected. HPV genotyping was performed by PCR. Comparing the HPV types found in circulation in the pre-vaccination (1999–2015) and post-vaccination periods (2020–2023), a statistically significant reduction in HPV 31 was noted, while the overall prevalence increased in the post-vaccination period. Besides the expected HPV positivity as a risk factor, the history of smoking was associated with LSIL or worse cytology at enrollment. For the first time, this population study revealed a statistically significant shift in the HPV genotype in the post-vaccination period, as well as the confirmation of risk factors for the development of abnormal cytology among Croatian women.

Source: Viruses - April 20, 2024 Category: Virology Authors: Ena Pe šut Ivana Šimić Rajko Fure š Nina Milutin Ga šperov Cvjetko Le ž Fabijan Feratovi ć Tomica Kukina Žvigač Magdalena Grce Ivana Erceg Ivko šić Ivan Sabol Tags: Article Source Type: research