Recontact to return new or updated PALB2 genetic results in the clinical laboratory setting

Conclusion
Novel pathogenic variants in PALB2 were identified in 18 individuals through retrospective gene panel testing. Recontacting these individuals regarding these new or updated findings had a range of outcomes. The process of conveying genomic results within this framework can be effectively accomplished while upholding patient autonomy, potentially leading to advantageous outcomes for patients and their families.

Source: Journal of Medical Genetics - April 19, 2024 Category: Genetics & Stem Cells Authors: Panchal, S., Mahajan, R., Aujla, N., McKay, P., Casalino, S., Di Gioacchino, V., Charames, G. S., Lefebvre, M., Metcalfe, K. A., Akbari, M. R., McCuaig, J. M., Lerner-Ellis, J. Tags: Cancer genetics Source Type: research