Iron and risk of dementia: Mendelian randomisation analysis in UK Biobank

Discussion
Genetic evidence supports a causal relationship between higher TSAT and risk of clinically defined non-AD and vascular dementia, in European and African groups. This association appears to be independent of apolipoprotein-E 4.

Source: Journal of Medical Genetics - April 19, 2024 Category: Genetics & Stem Cells Authors: Casanova, F., Tian, Q., Atkins, J. L., Wood, A. R., Williamson, D., Qian, Y., Zweibaum, D., Ding, J., Melzer, D., Ferrucci, L., Pilling, L. C. Tags: Open access Neurogenetics Source Type: research