Two New Phenylpropanoid Compounds from Lilium Brownii  and Their Anti-monoamine Oxidase Activity

Chem Biodivers. 2024 Apr 18:e202400524. doi: 10.1002/cbdv.202400524. Online ahead of print.ABSTRACTBaihe is a commonly used Chinese medicine for the treatment of neurological disorders. Clinically, the bulbs of Lilium brownii are used to act as Baihe. In the study, two new phenylpropanoid compounds including 3-O-acetyl-1-O-caffeoylglycerol (1) and 3-O-acetyl-1-O-p-coumaroylglycerol (2) were isolated from the bulbs of L. brownii. Their structures were identified by spectroscopic method and the effect on monoamine oxidase activity was determined using an enzyme labeling method. The results show 1 and 2 have anti-monoamine oxidase activity with 20.96% and 22.31% inhibition rates at 50 μg/ml, respectively.PMID:38634793 | DOI:10.1002/cbdv.202400524
Source: Chemistry and Biodiversity - Category: Biochemistry Authors: Source Type: research