Genomic landscape and clinical features of advanced thyroid carcinoma: a national database study in Japan

CONCLUSION: Genetic abnormalities with treatment options were found in 62.7% of advanced thyroid carcinomas. TP53 abnormality was an independent poor prognostic factor for overall survival in differentiated thyroid carcinoma. The time to treatment failure for lenvatinib was not different based on genetic profile.PMID:38630010 | DOI:10.1210/clinem/dgae271

Source: The Journal of Clinical Endocrinology and Metabolism - April 17, 2024 Category: Endocrinology Authors: Soji Toda Yukihiko Hiroshima Hiroyuki Iwasaki Katsuhiko Masudo Source Type: research