Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model

CONCLUSION: cGRP78 vaccines generated potent immunotherapeutic effects in a breast cancer mouse model. This novel strategy of targeting the GRP78 protein can promote the development of cancer vaccines and immunotherapies for breast cancer malignancies.PMID:38505675 | PMC:PMC10945302 | DOI:10.34172/bi.2023.27829

Source: BioImpacts - March 20, 2024 Category: Research Authors: Hamed Zare Hamid Bakherad Arman Nasr Esfahani Mohamad Norouzi Hossein Aghamollaei Seyed Latif Mousavi Gargari Fatemeh Mahmoodi Mahdi Aliomrani Walead Ebrahimizadeh Source Type: research