The role and mechanism of PDZ binding kinase in hypobaric and hypoxic acute lung injury

CONCLUSIONS: Overexpression of PBK inhibits the expression of p53 and activates SIRT1-PINK1 axis mediated mitochondrial autophagy to alleviate HHALI.PMID:38617778 | PMC:PMC11009593 | DOI:10.21037/jtd-24-188

Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Linao Sun Haoran Yue Hao Fang Runze Li Shicong Li Jianyao Wang Pengjie Tu Fei Meng Wang Yan Jinxia Zhang Elena Bignami Kyeongman Jeon Biniam Kidane Peng Zhang Source Type: research