2,4-dinitrophenol enhances cisplatin and etoposide cytotoxic activity on prostate cancer cell line

CONCLUSIONS: The enhanced cytotoxic effect of chemotherapeutics by 2,4-DNP may be the result of disturbed redox balance, reduced ability of cells to repair DNA, and the oxidative metabolic phenotype of prostate cancer cells.PMID:38549475 | DOI:10.26444/aaem/174919

Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Grzegorz Adamczuk Ewelina Humeniuk Kamila Adamczuk Aneta Grabarska Barbara Madej-Czerwonka Mariola Michalczuk Agnieszka Korga-Plewko Jaros ław Dudka Source Type: research