Construction and validation of a folate metabolism-related gene signature for predicting prognosis in HNSCC

ConclusionsOur study identified a novel and robust folate metabolic signature. A folate metabolic signature comprising six genes was effective in assessing the prognosis and reflecting the immune status of HNSCC patients. The target molecule of folate metabolic reprogramming, SHMT2, probably plays a very important role in HNSCC development and immune escape.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research