Mitovesicles secreted into the extracellular space of brains with mitochondrial dysfunction impair synaptic plasticity

Hypometabolism tied to mitochondrial dysfunction occurs in the aging brain and in neurodegenerative disorders, including in Alzheimer ’s disease, in Down syndrome, and in mouse models of these conditions. We ha...

Source: Molecular Neurodegeneration - April 14, 2024 Category: Neurology Authors: Pasquale D ’Acunzo, Elentina K. Argyrousi, Jonathan M. Ungania, Yohan Kim, Steven DeRosa, Monika Pawlik, Chris N. Goulbourne, Ottavio Arancio and Efrat Levy Tags: Research article Source Type: research