N-glycosylation of SCAP exacerbates hepatocellular inflammation and lipid accumulation via ACSS2-mediated histone H3K27 acetylation

In conclusion, SCAP N-glycosylation aggravates inflammation and lipid accumulation through enhancing ACSS2-mediated H3K27ac in hepatocytes.PMID:38591127 | DOI:10.1152/ajpgi.00273.2023

Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - April 9, 2024 Category: Physiology Authors: Xuemei Li Xiaoqin Tang Yue Xiang Zhibo Zhao Yanping Li Qiuying Ding Linkun Zhang Jingyuan Xu Lei Zhao Yao Chen Source Type: research