Ginsenoside Rh4 Facilitates the Sensitivity of Renal Cell Carcinoma to Ferroptosis via the NRF2 Pathway

CONCLUSIONS: Rh4 made RCC cells more sensitive to ferroptosis by inhibiting the NRF2 signaling and suppressing the expression of antioxidant enzymes. Therefore, combining Rh4 with ferroptosis-inducing reagents to treat RCC had potential therapeutic application.PMID:38583003 | DOI:10.56434/j.arch.esp.urol.20247702.16

Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Huandong Zhao Ruimin Ding Jiarui Han Source Type: research