Suction rectal biopsy (SRB) in Hirschsprung's Disease: Is a single macroscopically adequate sample sufficient?

In conclusion, single sample SRBs can be adequately diagnostic and cost-effective in low-resource settings, providing valuable insights for healthcare facilities in Malaysia and other developing countries. The use of adjunctive techniques such as calretinin staining may improve diagnostic accuracy while maintaining cost-effectiveness. Further prospective studies with larger sample sizes are needed to validate these findings.PMID:38155386

Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: P K Bal S A Nah W M R Wan Mohamad Noor M T Md Nor S Singaravel W S Tan Y W Tan A Sanmugam Source Type: research