IL-6 and IL-10 Levels in Rats Blood Plasma as Immune Responses Post Radioiodine (I-131) Administration

CONCLUSION: The highest increase in IL-6 and IL-10 levels occurred respectively in the first 0.5 hours 8 times and in the first 0.25 hours 1.47 times compared to controls. Internal irradiation with radioiodine resulted in a significant increase in immune cells in exposed blood plasma characterized by the production of the cytokines IL-6 and IL-10. This appears to be a response of immune cells to reduce or stop inflammatory reactions through the release of anti-inflammatory cytokines in an effort to prevent excessive inflammatory responses that can damage cells and tissues.PMID:38546084 | DOI:10.31557/APJCP.2024.25.3.1017

Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Harry Nugroho Eko Surniyantoro - Abinawanto Anom Bowolaksono Mukh Syaifudin Fadhillah Fadhillah Retno Lestari Teja Kisnanto Dwi Ramadhani Indra Saptiama Iin Kurnia Hasan Basri Triningsih Triningsih Bisma Barron Patrianesha Source Type: research