Investigating Neurometabolites and Pain in Fibromyalgia

Fibromyalgia (FM) is a complex, chronic pain disorder characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and cognitive difficulties. The exact cause of FM remains elusive, with factors like abnormal pain processing and central nervous system sensitization implicated in its pathophysiology. One hypothesis is that the immune system is frequently activated, prompting microglia to initiate a central inflammatory state. The purpose of this study was to use whole-brain magnetic resonance spectroscopic imaging (MRSI) to investigate whether abnormal inflammation in the central nervous system may be associated with symptoms of FM.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research