Genetic Architecture of Chronic Back Pain: A Multi-Ancestry Genome-Wide Association Study in The Million Veteran Program

This multi-ancestry meta-analysis of genome-wide association studies investigated the genetic factors underlying chronic back pain (CBP) in a large and diverse sample from the Million Veteran Program. A total of 553,601 Veterans of African (19.2%), European (72.6%) and Hispanic (8.2%) ancestry were included. The results revealed 87 loci (67 novel) with 90 independent variants. 85 variants had available summary statistics in (Bjornsdottir, 2023). 57 replicated at the nominal significance threshold (p
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research