Association of an impaired GH-IGF-I axis with cardiac wasting in patients with advanced cancer

ConclusionIn advanced cancer, reduced LVmass is associated with increased plasma GH and reduced IGF-I/GH ratio, suggesting increasing GH resistance, especially for patients with wasting syndrome with unintentional weight loss. Higher baseline IGF-I was associated  with a decrease in relative LVmass during follow-up.Graphical abstract
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research