Myocardial Blood Flow Assessment with PET Improves Risk Stratification Among HT Recipients with CAV1

Purpose: Cardiac allograft vasculopathy (CAV) results in impaired blood flow in epicardial vessels and/or coronary microvasculature. ISHLT CAV guidelines stratify disease into 4 groups based on severity of epicardial disease measured by coronary angiography (CA), with mild CAV (CAV 1) encompassing a broad phenotype, from luminal irregularities up to 69% stenosis of a primary vessel. Studies have shown that impaired myocardial blood flow (MBFR ≤ 2, CFR25) is associated with increased mortality risk.

Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , E.S. Harris, D. Skoll, J. Fried, V.S. Topkara, J. Raikhelkar, E.M. DeFilippis, F. Latif, M. Yuzefpolskaya, P.C. Colombo, G. Sayer, N. Uriel, A.J. Einstein, K.J. Clerkin Source Type: research