Spectral and Intrabreath Oscillometry for Early Diagnosis of Chronic Lung Allograft Dysfunction

Purpose: Chronic lung allograft dysfunction (CLAD) is the main obstacle to long-term survival after lung transplantation (LTx). CLAD is suspected when the forced expiratory volume in 1 second (FEV1) falls to ≤ 80% of the baseline value but is not confirmed until it is sustained for at least 3 months and other causes are ruled out. Oscillometry is a highly sensitive pulmonary function test (PFT) modality. The current study investigated whether oscillometry is associated with CLAD at the initial ≥20% drop in FEV1.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research