Plasma and Bronchoalveolar Fluid Proteomes Identify Similar Pathways Associated with Allograft Dysfunction in Individual LTx Recipients with Different Underlying Conditions

Purpose: Proteomic analysis of plasma and bronchoalveolar lavage fluid (BALF) from lung transplant (LTx) recipients may identify potential biomarkers or pathways associated with allograft dysfunction. We conducted N-of-1 studies of 2 CF and 1 PH LTx recipients, and examined whether longitudinal changes in blood and BAL shed light on the molecular underpinnings of allograft dysfunction specific to CF.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research