Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology

DISCUSSION: Hippocampal degeneration is differentially sensitive to SVD and Aβ pathology. The pattern of hippocampal atrophy could serve as a disease-specific biomarker, and thus guide clinical diagnosis and individualized treatment strategies for mixed dementia.PMID:38574400 | DOI:10.1002/alz.13791

Source: The Journal of Alzheimers Association - April 4, 2024 Category: Psychiatry Authors: Kristiana Xhima Julie Ottoy Erin Gibson Katherine Zukotynski Christopher Scott Ginelle J Feliciano Sabrina Adamo Phillip H Kuo Michael J Borrie Howard Chertkow Richard Frayne Robert Laforce Michael D Noseworthy Frank S Prato Demetrios J Sahlas Eric E Smit Source Type: research