Rho kinase inhibitor Y27632 promotes survival of human induced pluripotent stem cells during differentiation into functional midbrain dopaminergic progenitor cells in < em > vitro < /em >

CONCLUSION: Treatment with Y27632 (5 μmol/L) for 24 h significantly promotes the survival of human iPSCs-NECs during their differentiation into DPAs without affecting the cell differentiation, which indirectly enhances the efficiency of cell differentiation.PMID:38501408 | PMC:PMC10954535 | DOI:10.12122/j.issn.1673-4254.2024.02.05
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Source Type: research