The role of polymorphic cytochrome P450 gene (CYP2B6) in B-chronic lymphocytic leukemia (B-CLL) incidence and outcome among Egyptian patients

In conclusion, our findings showed that the CYP2B6*9 (G516T) polymorphism is associated with B-CLL susceptibility among Egyptian patients. This variant greatly affected the clinical outcome and can serve as a good therapeutic marker in predicting response to cyclophosphamide treatment.PMID:38560574 | PMC:PMC10972729 | DOI:10.32604/or.2024.047021

Source: Oncology Research - April 1, 2024 Category: Cancer & Oncology Authors: Menna Al-Adl Magdy M Youssef Ahmed El-Sebaie Sherif Refaat Afaf El-Said Source Type: research