Histone methyltransferase Suv39h1 regulates hepatic stellate cell activation and is targetable in liver fibrosis

Conclusions
Our data demonstrate a previously unrecognised role for Suv39h1 in liver fibrosis and offer proof-of-concept of its targetability in the intervention of cirrhosis.

Source: Gut - April 5, 2024 Category: Gastroenterology Authors: Kong, M., Zhou, J., Kang, A., Kuai, Y., Xu, H., Li, M., Miao, X., Guo, Y., Fan, Z., Xu, Y., Li, Z. Tags: Gut Hepatology Source Type: research