Metformin Suppresses Both PD-L1 Expression in Cancer Cells and Cancer-Induced PD-1 Expression in Immune Cells to Promote Antitumor Immunity
CONCLUSIONS: Metformin blocks both PD-L1 and PD-1 within the tumor microenvironment. This study provided a mechanistic insight into the efficacy of metformin in improving immunotherapy in human cancer.PMID:38529546 | DOI:10.3343/alm.2023.0443
Source: Annals of Laboratory Medicine - Category: Laboratory Medicine Authors: Su Hwan Park Juheon Lee Hye Jin Yun Seok-Ho Kim Jong-Ho Lee Source Type: research
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