Commentary on “Study Partner Report of Apathy in Older Adults is Associated with AD Biomarkers: Findings from the Harvard Aging Brain Study”
Apathy, characterized by a reduction in self-initiated or goal-directed activity, is the most common neuropsychiatric symptom in Alzheimer's disease (AD), with a prevalence between 43-59% across stages of dementia (1). Apathy is linked to a progression from normal cognition to mild cognitive impairment (MCI) or from MCI to dementia (2). Across clinical stages of AD, apathy increases functional impairment, mortality, and caregiver stress (2).
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Siddharth Khasnavis, Ryan S. O'Dell, Christopher H. van Dyck, Adam P. Mecca Tags: Editorial Source Type: research