A WNT mimetic with broad spectrum FZD-specificity decreases fibrosis and improves function in a pulmonary damage model

CONCLUSIONS: Our results highlight the unexpected capacity of a WNT mimetic to effect tissue repair after lung damage and support the continued development of Wnt/β-catenin pathway modulation for the treatment of pulmonary fibrosis.PMID:38566174 | DOI:10.1186/s12931-024-02786-2

Source: Cell Research - April 2, 2024 Category: Cytology Authors: Mehaben Patel Yorick Post Natalie Hill Asmiti Sura Jay Ye Trevor Fisher Nicholas Suen Mengrui Zhang Leona Cheng Ariel Pribluda Hui Chen Wen-Chen Yeh Yang Li H élène Baribault Russell B Fletcher Source Type: research