Ready for Renascence in Mosquito: The Regulation of Gene Expression in Plasmodium Sexual Development

Acta Trop. 2024 Mar 28:107191. doi: 10.1016/j.actatropica.2024.107191. Online ahead of print.ABSTRACTMalaria remains one of the most perilous vector-borne infectious diseases for humans globally. Sexual gametocyte represents the exclusive stage at which malaria parasites are transmitted from the vertebrate to the Anopheles host. The most effective approach to prevent malaria transmission is by addressing the sexual developmental processes, that is, gametocytogenesis and gametogenesis. Thus, this review will comprehensively cover advances in the regulation of gene expression surrounding the transmissible stages, including epigenetic, transcriptional, and post-transcriptional control.PMID:38554994 | DOI:10.1016/j.actatropica.2024.107191
Source: Acta Tropica - Category: Infectious Diseases Authors: Source Type: research