Identification and validation of tryptophan metabolism-related lncRNAs in lung adenocarcinoma prognosis and immune response

ConclusionWe constructed a new prognostic model for tryptophan metabolism-related lncRNA. The risk score was closely associated with common clinical features such as immune cell infiltration, immune-related function, TMB, and anticancer drug sensitivity. Knockdown of ZNF8-ERVK3-1 inhibited LUAD cell proliferation, migration, invasion, and G0/G1 phase blockade and promoted apoptosis.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research