Concentration of trace elements in blood of Polish patients with prostate cancer

Environ Toxicol Pharmacol. 2024 Mar 27:104425. doi: 10.1016/j.etap.2024.104425. Online ahead of print.ABSTRACTThe goal of the study was to analyse the concentrations of chemical elements (Fe, Ni, As, Cd, Pb, Hg, Cr, Zn) which are important for the determination of environmental toxins (e.g. resulting from smoking, exposure to harmful agents at work) in Polish patients with prostate cancer. The study covered 66 patients with diagnosed prostate cancer and 64 healthy volunteers over 50 years old. The analysis of the concentrations of selected chemical elements in whole blood was performed using inductively coupled plasma mass spectrometry (ICP-MS). In their blood, the patients with cancer had a significantly higher concentration of only one of the examined elements: arsenic. Additionally, the study group had lower concentrations of chromium, zinc, but also cadmium and lead, which are commonly regarded as carcinogenic. Taking into consideration the control group of healthy subjects of this study, we can assume that the subjects with prostate cancer were exposed to higher levels of arsenic, and that exposure to this element may be associated with an increased risk of cancer.PMID:38552756 | DOI:10.1016/j.etap.2024.104425
Source: Cancer Control - Category: Cancer & Oncology Authors: Source Type: research