Acute Lymphoblastic Leukemia With Near-haploid Karyotype and Philadelphia Chromosome

CONCLUSION: The coexistence of the BCR::ABL1 chimera and near-haploidy in the same cytogenetic clone suggested a possible synergistic role in leukemogenesis, with the former activating signaling pathways and the latter disrupting gene dosage balance.PMID:38537997 | DOI:10.21873/anticanres.16935

Source: Cell Research - March 27, 2024 Category: Cytology Authors: Ioannis Panagopoulos Kristin Andersen Hilde Skuterud Wik Maren Randi Tands æther Source Type: research