Patterns of recurrence and disease progression in patients with positive-margin olfactory neuroblastoma following primary resection

CONCLUSIONS: Approximately half of patients with positive-margin ONB may experience disease recurrence. Patients with an advanced disease stage (Kadish D) may have a higher likelihood of developing recurrence/progression. Furthermore, patients with tumor burden following resection (STR and Kadish D) may have worse OS. However, in positive-margin ONB with no gross disease following initial resection, the presence of disease recurrence does not significantly alter survival when receiving salvage therapy.PMID:38518294 | DOI:10.3171/2024.1.JNS23730

Source: Journal of Neurosurgery - March 22, 2024 Category: Neurosurgery Authors: Megan M J Bauman Jeffrey P Graves Travis J Haller Ryan A McMillan David M Routman Aditya Raghunathan Janalee K Stokken Michael J Link Eric J Moore Garret Choby Jamie J Van Gompel Source Type: research