Normobaric hyperoxia alleviates complement C3-mediated synaptic pruning and brain injury after intracerebral hemorrhage

CONCLUSIONS: Our results revealed that NBO exerts its neuroprotective effects by reducing C3-mediated synaptic pruning, which suggested that NBO therapy could be used for the clinical treatment of ICH.PMID:38532579 | PMC:PMC10966135 | DOI:10.1111/cns.14694

Source: CNS Neuroscience and Therapeutics - March 27, 2024 Category: Neuroscience Authors: Moxin Wu Kai Chen Yasong Zhao Min Jiang Bing Bao Wenmin Yu Zhiying Chen Xiaoping Yin Source Type: research