Assessment of Circulating Tumor Cells in Colorectal Cancer as an Adjunctive Non-invasive Diagnostic Method

CONCLUSION: This study assessed the diagnostic potential of CTC examination in CRC as an adjunctive diagnostic method using the subjective manual identification method and laser capture microdissection at 40x magnification. Despite the limitations associated with subjective cell counting, the results showed 50% sensitivity and 88.89% specificity in diagnosing CRC. Further studies are needed to optimize the manual identification process and validate the clinical utility of CTC analysis in CRC patients.PMID:38213054

Source: Acta medica Indonesiana - January 12, 2024 Category: Internal Medicine Authors: Saskia Aziza Nursyirwan Murdani Abdullah Andri Sanityoso Sulaiman Ikhwan Rinaldi Dadang Makmun Marcellus Simadibrata Dimas Ramadhian Noor Agustinus Wiraatmadja Wifanto Saditya Jeo Nur Rahadiani Diah Rini Handjari Hamzah Shatri Source Type: research